Primary Identifier | MGI:2679721 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 330938 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein domain specific binding activity. Involved in several processes, including forebrain development; modification of postsynaptic actin cytoskeleton; and regulation of cytoskeleton organization. Is active in cytosol; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; autonomic nervous system; central nervous system; embryo mesenchyme; and sensory organ. Orthologous to human DIXDC1 (DIX domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced spontaneous locomotor activity, abnormal behavior in the elevated plus maze, and deficits in startle reactivity. [provided by MGI curators] |