Primary Identifier | MGI:2445031 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235344 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in several processes, including protein phosphorylation; regulation of insulin receptor signaling pathway; and regulation of primary metabolic process. Acts upstream of or within insulin receptor signaling pathway. Located in cytoplasm and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and heart. Orthologous to human SIK2 (salt inducible kinase 2). PHENOTYPE: Mice heterozygous for a knock-out allele exhibit darkened hair color in an agouti background. [provided by MGI curators] |