Primary Identifier | MGI:1921013 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235345 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in axoneme assembly; flagellated sperm motility; and spermatogenesis. Located in cilium and cytoplasm. Is expressed in embryo and lung. Orthologous to human HOATZ (HOATZ cilia and flagella associated protein). PHENOTYPE: Mice homozygous for a null allele develop hydrocephalus, male infertility, oligo-astheno-terato-zoospermia, and disorganized axonemes in epdendymal cilia and sperm flagellum. [provided by MGI curators] |