Primary Identifier | MGI:2685363 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 244882 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process; phospholipid transport; and positive regulation of ERK1 and ERK2 cascade. Located in cytoplasm and plasma membrane. Orthologous to human TNFAIP8L3 (TNF alpha induced protein 8 like 3). PHENOTYPE: Mice homozygous for a null allele show delayed skin tumor onset and reduced tumor size after chemical induction with a carcinogen. [provided by MGI curators] |