Primary Identifier | MGI:2388361 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235379 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein binding activity involved in heterotypic cell-cell adhesion. Acts upstream of or within clustering of voltage-gated sodium channels and microvillus organization. Located in extracellular space and plasma membrane. Is expressed in several structures, including genitourinary system; heart; lung; skeletal muscle; and spleen. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human GLDN (gliomedin). PHENOTYPE: Mice homozygous for a knock-out allele fail to form heminodes without overt neurological abnormalities or alteration in nerve conduction. [provided by MGI curators] |