Primary Identifier | MGI:2384571 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235415 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SNARE binding activity and neurotransmitter transmembrane transporter activity. Involved in insulin secretion; regulation of synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle exocytosis. Acts upstream of or within regulation of neurotransmitter secretion. Located in cytosol; plasma membrane; and synapse. Is active in photoreceptor ribbon synapse; presynaptic active zone membrane; and synaptic vesicle membrane. Is expressed in brain; cerebral cortex; and cortical layer V. Orthologous to human CPLX3 (complexin 3). PHENOTYPE: Mice homozygous for a null allele are fertile, viable and exhibit normal synaptic transmission. [provided by MGI curators] |