Primary Identifier | MGI:2444277 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 320563 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in positive regulation of axon extension. Located in cell surface. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit perinatal lethality, absent tail pinch response, and defective peroneal and tibial nerve morphology and branch extension. [provided by MGI curators] |