| Primary Identifier | MGI:1914537 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 67287 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable NAD+-protein ADP-ribosyltransferase activity; kinase binding activity; and protein serine/threonine kinase activator activity. Predicted to be involved in endoplasmic reticulum unfolded protein response; positive regulation of dendrite morphogenesis; and protein auto-ADP-ribosylation. Predicted to be active in endoplasmic reticulum tubular network and nuclear envelope. Is expressed in nervous system and sensory organ. Orthologous to human PARP6 (poly(ADP-ribose) polymerase family member 6). PHENOTYPE: Homozygous mice with an allele devoid of catalytic activity die shortly after birth with cyanosis and less air in lungs. A small percentage survive to at least P21, are smaller, have erratic and jumpy behavior and one male surviving to adulthood is sterile. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
