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Protein Coding Gene : Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type
Primary Identifier  MGI:1919327 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  72077
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity. Acts upstream of or within intestinal absorption; kidney morphogenesis; and tissue morphogenesis. Predicted to be located in Golgi membrane. Orthologous to human GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type).
PHENOTYPE: Homozygote null mice have decreases in core 2 O-glycan structures on cell surfaces, decreased immunoglobulin levels, and disrupted mucosal barrier in the intestines. [provided by MGI curators]
  • synonyms:
  • MGI:1917325,
  • RIKEN cDNA 2210401J11 gene,
  • RIKEN cDNA 2210021I22 gene,
  • RIKEN cDNA 2010013H22 gene,
  • 2010013H22Rik,
  • Gcnt3,
  • MGI:1917367,
  • glucosaminyl (N-acetyl) transferase 3, mucin type,
  • 2210021I22Rik,
  • 2210401J11Rik
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