| Primary Identifier | MGI:2142908 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 102371 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA polymerase II complex binding activity. Involved in intracellular signal transduction. Located in I band and cytoplasmic side of plasma membrane. Colocalizes with cortical actin cytoskeleton. Is expressed in heart; lung; and vascular system. Orthologous to several human genes including MYZAP (myocardial zonula adherens protein). PHENOTYPE: Homozygous KO results in a maladaptive response to increased biomechanical stress, resulting in adverse cardiac remodeling, contractile dysfunction, heart failure, and increased mortality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
