Primary Identifier | MGI:1355315 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 50875 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables tropomyosin binding activity. Acts upstream of or within actin cytoskeleton organization; erythrocyte development; and positive regulation of mitotic cell cycle phase transition. Located in striated muscle thin filament. Is expressed in several structures, including alimentary system; brain; heart; metanephros; and sensory organ. Orthologous to human TMOD3 (tropomodulin 3). PHENOTYPE: Mice homozygous for a gene trap allele exhibit lethality during fetal development with anemia due to impaired erythroid terminal differentiation in the fetal liver. [provided by MGI curators] |