Primary Identifier | MGI:1355335 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 50876 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity and tropomyosin binding activity. Acts upstream of or within learning or memory; neuron-neuron synaptic transmission; and positive regulation of G protein-coupled receptor signaling pathway. Predicted to be located in growth cone. Predicted to be active in striated muscle thin filament. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; nervous system; and notochord. Orthologous to human TMOD2 (tropomodulin 2). PHENOTYPE: Homozygous mutation of this gene results in enhanced LTP, hyperactivity, impaired startle response, and impaired learning. [provided by MGI curators] |