Primary Identifier | MGI:2445221 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235505 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transforming growth factor beta binding activity. Acts upstream of or within several processes, including negative regulation of cell population proliferation; osteoclast fusion; and regulation of keratinocyte differentiation. Located in extracellular space. Is expressed in brain; notochord; and nucleus pulposus. Orthologous to human CD109 (CD109 molecule). PHENOTYPE: Mice homozygous for a null mutation display epidermal hyperplasia and thickening, sebaceous gland hyperplasia and transient impairment of hair growth. [provided by MGI curators] |