Primary Identifier | MGI:97566 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 109785 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables phosphoacetylglucosamine mutase activity. Acts upstream of or within UDP-N-acetylglucosamine biosynthetic process; hemopoiesis; and spermatogenesis. Is expressed in colon; metanephros; ovary; and testis. Human ortholog(s) of this gene implicated in immunodeficiency 23 and teratoma. Orthologous to human PGM3 (phosphoglucomutase 3). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit male infertility, anemia, leukopenia, thrombocytopenia, abnormal pancreatic and salivary gland morphology, and splenomegaly. [provided by MGI curators] |