| Primary Identifier | MGI:2679732 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 331004 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in several processes, including monoatomic cation transmembrane transport; phagosome maturation; and regulation of intracellular pH. Located in early phagosome; phagocytic vesicle membrane; and plasma membrane. Is expressed in several structures, including ear; hemolymphoid system; nervous system; tail somite; and urinary system. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human SLC9A9 (solute carrier family 9 member A9). PHENOTYPE: Mice homozygous for a null allele display abnormal social and olfactory behavior, abnormal CNS synaptic transmission, impaired synaptic vesicle exocytosis, impaired presynaptic calcium entry, and decreased synaptic vescile pH. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
