Primary Identifier | MGI:1928480 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 56318 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables thiamine phosphate phosphatase activity. Involved in nucleobase-containing small molecule metabolic process; regulation of sensory perception of pain; and thiamine metabolic process. Located in filopodium; plasma membrane; and vesicle membrane. Is expressed in epithelium of phallic urethra of female; epithelium of phallic urethra of male; genital tubercle mesenchyme of female; and urethral plate. Used to study prostate cancer. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human ACP3 (acid phosphatase 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased thermal nociceptive threshold and mechanical allodynia in chronic inflammatory and nerve injury pain models. [provided by MGI curators] |