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Protein Coding Gene : Twf2 twinfilin actin binding protein 2
Primary Identifier  MGI:1346078 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  23999
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables actin monomer binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in barbed-end actin filament capping and sequestering of actin monomers. Located in several cellular components, including lamellipodium; myofibril; and stereocilium. Is expressed in several structures, including ear; early embryo; genitourinary system; nervous system; and respiratory system. Orthologous to human TWF2 (twinfilin actin binding protein 2).
PHENOTYPE: Mice homozygous for a targeted allele are viable, fertile, and do not display obvious morphological or behavioral abnormalities. [provided by MGI curators]
  • synonyms:
  • Ptk9l,
  • Twf2,
  • protein tyrosine kinase 9-like (A6-related protein),
  • expressed sequence AU014993,
  • twinfilin actin binding protein 2,
  • AU014993,
  • Twinfilin-2,
  • A6-related,
  • MGI:2143188
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