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Protein Coding Gene : Nckipsd NCK interacting protein with SH3 domain
Primary Identifier  MGI:1931834 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  80987
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable Arp2/3 complex binding activity. Involved in positive regulation of neuron projection development. Predicted to be located in glutamatergic synapse and postsynapse. Predicted to be part of COP9 signalosome. Is expressed in central nervous system and retina. Orthologous to human NCKIPSD (NCK interacting protein with SH3 domain).
PHENOTYPE: Mice homozygous for a null mutation exhibit altered protein composition of postsynaptic densities and actin cytoskeleton in hippocampal neurons. [provided by MGI curators]
  • synonyms:
  • AF3P21,
  • Nckipsd,
  • Wasbp,
  • WISH,
  • NCK interacting protein with SH3 domain,
  • DIP1,
  • Wiskott-Aldrich syndrome homolog (human) binding protein,
  • ORF1,
  • SPIN90
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Trail: ProteinCodingGene

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