| Primary Identifier | MGI:2176375 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 171530 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled receptor binding activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; hormone-mediated signaling pathway; and negative regulation of gonadotropin secretion. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human UCN2 (urocortin 2). PHENOTYPE: Female, but not male, mice homozygous for a null allele show a significant increase in the basal daily rhythms of ACTH and corticosterone, altered drinking and feeding responses, and increased antidepressant-like behavior. Mice homozygous for a second null allele show normal social memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
