Primary Identifier | MGI:2447303 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235631 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable threonine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Predicted to be active in endoplasmic reticulum. Is expressed in heart and pericardium and liver. Orthologous to human PRSS50 (serine protease 50). PHENOTYPE: Mice homozygous for a null allele exhibit decreased male fertility with reduced litter sizes and teratozoospermia with reduced sperm motility and abnormal sperm heads and tails. [provided by MGI curators] |