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Protein Coding Gene : Mobp myelin-associated oligodendrocytic basic protein
Primary Identifier  MGI:108511 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  17433
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

A structural constituent of myelin sheath. Predicted to be involved in central nervous system myelin formation. Located in mitochondrion. Is expressed in central nervous system and eye. Human ortholog(s) of this gene implicated in frontotemporal dementia. Orthologous to human MOBP (myelin associated oligodendrocyte basic protein).
PHENOTYPE: Mice homozygous for one null allele show abnormal myelin arrangements but do not exhibit an overt behavorial phenotype. Mice homozygous for another allele have normal myelin. [provided by MGI curators]
  • synonyms:
  • R74645,
  • AI835053,
  • AI839848,
  • MGD-MRK-37555,
  • MGI:2143445,
  • myelin-associated oligodendrocytic basic protein,
  • expressed sequence AI839848,
  • MOBP155,
  • MGI:2143124,
  • Mobp,
  • expressed sequence R74645,
  • MGI:2143130,
  • expressed sequence AI835053
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