Primary Identifier | MGI:2143103 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 102566 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium-activated cation channel activity and intracellularly calcium-gated chloride channel activity. Predicted to be involved in chloride transmembrane transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; sensory organ; skin; and viscerocranium. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 10. Orthologous to human ANO10 (anoctamin 10). PHENOTYPE: Mice homozygous for a knock-out allele fail to exhibit calcium-activated chloride ion secretion in the jejunum. [provided by MGI curators] |