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Protein Coding Gene : Ano10 anoctamin 10

Primary Identifier  MGI:2143103 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  102566
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable calcium-activated cation channel activity and intracellularly calcium-gated chloride channel activity. Predicted to be involved in chloride transmembrane transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; sensory organ; skin; and viscerocranium. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 10. Orthologous to human ANO10 (anoctamin 10).
PHENOTYPE: Mice homozygous for a knock-out allele fail to exhibit calcium-activated chloride ion secretion in the jejunum. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI604832,
  • Tmem16k,
  • Ano10,
  • anoctamin 10,
  • AI604832,
  • transmembrane protein 16K

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For