| Primary Identifier | MGI:1934860 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 93730 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Acts upstream of or within flagellated sperm motility and spermatogenesis. Located in cilium; cytoplasm; and manchette. Is expressed in several structures, including brain; sensory organ; testis; and upper jaw incisor. Used to study Bardet-Biedl syndrome 17. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 17. Orthologous to human LZTFL1 (leucine zipper transcription factor like 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit obesity, ventriculomegaly, decreased ERG a- and b-wave amplitudes, retinal degeneration, and reduced male fertility associated with decreased sperm number and sperm motility and abnormal sperm morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
