Primary Identifier | MGI:2676852 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 387183 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including bone marrow development; regulation of fat cell differentiation; and regulation of osteoblast differentiation. Is expressed in cranial ganglion; dorsal root ganglion; and neural retina. Orthologous to human MIR188 (microRNA 188). PHENOTYPE: Mice homozygous for one targeted deletion are viable with no observed pathologies. Mice homozygous for a different allele exhibit increased bone formation and ossification swith increased osteoblasts and reduced adipocyte differentiation. [provided by MGI curators] |