Primary Identifier | MGI:1925435 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 78185 |
Mgi Type | lncRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within cellular response to interleukin-2 and chromatin organization. Located in nucleus. PHENOTYPE: Homozygous knockout mice of this negative regulator of Foxp3 show decreased susceptibility to autoimmune diabetes and reduced severity of insulitis. [provided by MGI curators] |