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Protein Coding Gene : Wdr13 WD repeat domain 13
Primary Identifier  MGI:1914661 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  73447
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables promoter-specific chromatin binding activity. Acts upstream of or within negative regulation of type B pancreatic cell proliferation. Predicted to be located in centriolar satellite; nucleoplasm; and plasma membrane. Is expressed in central nervous system and retina. Orthologous to human WDR13 (WD repeat domain 13).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased pancreas beta cell proliferation, hyperinsulinemia and mild obesity. [provided by MGI curators]
  • synonyms:
  • expressed sequence W51679,
  • DNA segment, Chr X, human S7467E, expressed,
  • Wdr13,
  • MGI:1920697,
  • W51679,
  • 5730411P10Rik,
  • 1700060B08Rik,
  • MGI:2148087,
  • RIKEN cDNA 1700060B08 gene,
  • mMg21,
  • RIKEN cDNA 5730411P10 gene,
  • MGI:1099465,
  • WD repeat domain 13,
  • DXHXS7467e
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