Primary Identifier | MGI:2384310 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 236732 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; miRNA binding activity; and single-stranded RNA binding activity. Acts upstream of or within negative regulation of RNA metabolic process; negative regulation of vascular associated smooth muscle cell proliferation; and positive regulation of vascular associated smooth muscle cell apoptotic process. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleolus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; oocyte; and sensory organ. Human ortholog(s) of this gene implicated in TARP syndrome; colorectal cancer; lung adenocarcinoma; and lung cancer. Orthologous to human RBM10 (RNA binding motif protein 10). PHENOTYPE: Male chimeras hemizygous for a gene trapped allele appear normal at E8.5. [provided by MGI curators] |