Primary Identifier | MGI:97516 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 18555 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein serine/threonine kinase activity. Involved in several processes, including regulation of insulin secretion involved in cellular response to glucose stimulus; secretion by cell; and spermatogenesis. Located in cytoplasm and plasma membrane. Colocalizes with synaptic vesicle. Is expressed in several structures, including alimentary system; early embryo; genitourinary system; immune system; and nervous system. Orthologous to human CDK16 (cyclin dependent kinase 16). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with asthenozoospermia and abnormal sperm morphology. [provided by MGI curators] |