Primary Identifier | MGI:2384312 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 236733 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type deubiquitinase activity; cysteine-type endopeptidase activity; and transcription corepressor binding activity. Predicted to be involved in protein deubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in brain; cortical plate; dorsal root ganglion; and spinal cord. Orthologous to human USP11 (ubiquitin specific peptidase 11). PHENOTYPE: Male mice hemizygous for a null allele display enlarged prostate glands and hyperplastic prostate gland epithelium. Female homozygous null mice are viable. [provided by MGI curators] |