Primary Identifier | MGI:1890216 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 56774 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables (R)-carnitine transmembrane transporter activity. Involved in (R)-carnitine transmembrane transport. Located in apical plasma membrane. Is expressed in large intestine and lung. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SLC6A14 (solute carrier family 6 member 14). PHENOTYPE: Mice hemizygous or homozygous for a null allele are viable, fertile and overtly normal. Homozygous females show normal plasma amino acid levels and mammary gland development but exhibit delayed development and reduced growth of mammary tumors in spontaneous mouse models of breast cancer. [provided by MGI curators] |