Primary Identifier | MGI:1888939 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 56526 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activity and molecular adaptor activity. Predicted to be involved in cytoskeleton-dependent cytokinesis and protein localization. Located in several cellular components, including cleavage furrow; septin cytoskeleton; and synaptic vesicle. Part of septin complex. Is active in presynapse. Is expressed in alimentary system; central nervous system; genitourinary system; sensory organ; and thymus. Orthologous to human SEPTIN6 (septin 6). PHENOTYPE: Homozygous females and hemizygous males harboring a knock-out mutation in this gene have a normal lifespan and display neither gross abnormalities, changes in cytokinesis, nor spontaneous malignancies including leukemia. [provided by MGI curators] |