Primary Identifier | MGI:2387585 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 208968 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in brain; dorsal root ganglion; early conceptus; and spinal cord. Orthologous to human ZNF280C (zinc finger protein 280C). PHENOTYPE: Homozygous null mice show reduced tumor burden and decreased high-grade adenomas following AOM/DSS induced colitis-associated cancer. [provided by MGI curators] |