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Protein Coding Gene : Plac1 placental specific protein 1
Primary Identifier  MGI:1926287 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  56096
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in placenta development. Acts upstream of or within spongiotrophoblast layer developmental growth. Predicted to be located in extracellular region. Is expressed in several structures, including body wall mesenchyme; brain; extraembryonic component; genitourinary system; and lung. Orthologous to human PLAC1 (placenta enriched 1).
PHENOTYPE: Female and male mice null for this gene display postnatal lethality with placental abnormalities. Female mice heterozygous for this allele display an enlarged placenta with expansion of the junctional zone. [provided by MGI curators]
  • synonyms:
  • DNA segment, Chr X, Wayne State University 72, expressed,
  • Oosp2l,
  • extraembryonic ectoderm and chorion sequence 26,
  • MGI:1860265,
  • MGI:106239,
  • ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 26,
  • Plac1,
  • MGD-MRK-33931,
  • DXWsu72e,
  • Epcs26,
  • placental specific protein 1
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