Primary Identifier | MGI:2685619 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 331416 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within acrosome reaction and penetration of zona pellucida. Predicted to be located in nucleus. Predicted to be active in synaptonemal complex. Is expressed in several structures, including gonad; liver; lung; muscle tissue; and spleen. Human ortholog(s) of this gene implicated in spermatogenic failure 4. Orthologous to human SYCP3 (synaptonemal complex protein 3). PHENOTYPE: Mice homozygous for a null allele exhibit reduced male fertility due to impaired penetration of zona pellucida. [provided by MGI curators] |