| Primary Identifier | MGI:2685211 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 245424 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and positive regulation of MAPK cascade. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in growth hormone secreting pituitary adenoma 2. Orthologous to human GPR101 (G protein-coupled receptor 101). PHENOTYPE: Homozygous null males exhibit hyperinsulinemia and reduced glucose tolerance, increased susceptibility to diet-induced obesity with increased adiposity, and hypothalamic microglial activity but impaired phagocytosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
