Primary Identifier | MGI:1933244 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 83553 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable thiamine pyrophosphate binding activity and transketolase activity. Predicted to be located in cytosol. Is expressed in early conceptus and secondary oocyte. Orthologous to human TKTL1 (transketolase like 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to DSS-induced colitis. Male mice homozygous for a mutation show normal fertility. [provided by MGI curators] |