Primary Identifier | MGI:97167 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 17698 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including actin binding activity; double-stranded RNA binding activity; and protein kinase binding activity. Acts upstream of or within positive regulation of podosome assembly. Located in several cellular components, including basolateral plasma membrane; microvillus; and uropod. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in immunodeficiency 50. Orthologous to human MSN (moesin). PHENOTYPE: Homozygous female and hemizygous male mutant mice develop normally and are fertile. No obvious histological abnormalities are reported. [provided by MGI curators] |