| Primary Identifier | MGI:2679720 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 278180 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable complement component C3b binding activity. Acts upstream of or within negative regulation of T cell proliferation and negative regulation of interleukin-2 production. Predicted to be part of protein-containing complex. Is expressed in bone marrow; oviduct; and thyroid gland. Orthologous to human VSIG4 (V-set and immunoglobulin domain containing 4). PHENOTYPE: Mice homozygous for a knock-out allele fail to exhibit complement-dependent clearance of Staphylococcus aureus from the circulation and are more susceptible to Listeria monocytogenes infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
