Primary Identifier | MGI:1926594 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 57385 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled UTP receptor activity. Acts upstream of or within cellular response to prostaglandin E stimulus and transepithelial chloride transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to be active in glutamatergic synapse and presynaptic active zone membrane. Is expressed in skeletal muscle. Orthologous to human P2RY4 (pyrimidinergic receptor P2Y4). PHENOTYPE: Homozygous and hemizygous null mice display abnormal digestive secretion and homozygous null females display partially penetrant lethality. [provided by MGI curators] |