Primary Identifier | MGI:1891915 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 54601 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sequence-specific DNA binding activity. Acts upstream of or within mitotic G2 DNA damage checkpoint signaling; negative regulation of cell population proliferation; and positive regulation of DNA-templated transcription. Predicted to be located in cytosol and nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including adipose tissue; central nervous system; early embryo; genitourinary system; and skeletal muscle. Orthologous to human FOXO4 (forkhead box O4). PHENOTYPE: Mice hemizygous and homozygous for a knock-out allele are viable, fertile and grossly normal with no detectable histological abnormalities in most tissues. [provided by MGI curators] |