| Primary Identifier | MGI:2685460 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 245536 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within transcription by RNA polymerase II. Orthologous to human CXorf65 (chromosome X open reading frame 65). PHENOTYPE: Germinal center B cell-specific homozygous knockout leads to protection from the autoimmune symptoms of experimentally-induced lupus because of increased B cell apoptosis. Overexpression leads to exacerbated symptoms because of suppressed apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
