| Primary Identifier | MGI:1914325 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 67075 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in cognition; magnesium ion transport; and protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum. Predicted to be part of oligosaccharyltransferase complex. Used to study primary immunodeficiency disease. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia and congenital disorder of glycosylation Icc. Orthologous to human MAGT1 (magnesium transporter 1). PHENOTYPE: Male mice hemizygous for one gene trap allele exhibit decreased T cell number and increased B cell numbers with increased activation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
