Primary Identifier | MGI:2685222 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 213439 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables bioactive lipid receptor activity. Acts upstream of or within T cell homeostasis. Predicted to be located in centriolar satellite and intracellular membrane-bounded organelle. Predicted to be active in plasma membrane. Orthologous to human GPR174 (G protein-coupled receptor 174). PHENOTYPE: Male mice hemizygous for a knock-out allele exhibit abnormal T cell proliferation, abnormal regulatory T cell physiology and decreased susceptibility to EAE. [provided by MGI curators] |