Primary Identifier | MGI:3029414 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 382236 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 93. Orthologous to human BRWD3 (bromodomain and WD repeat domain containing 3). PHENOTYPE: Male chimeras hemizygous for a gene trapped allele exhibit short tail buds, microcephaly and, in some cases, embryonic growth retardation. [provided by MGI curators] |