Primary Identifier | MGI:3642445 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 100039319 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be a structural constituent of chromatin. Predicted to be involved in heterochromatin formation. Predicted to be located in euchromatin. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H2AB1 (H2A.B variant histone 1); H2AB2 (H2A.B variant histone 2); and H2AB3 (H2A.B variant histone 3). PHENOTYPE: Male mice hemizygous for knock-out alleles of H2afb1, H2afb2 and H2afb3 exhibit reduced fertility, teratozoospermia, oligozoospermia and clogged seminiferous tubules. [provided by MGI curators] |