Primary Identifier | MGI:1929885 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 64103 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within endothelial cell morphogenesis; negative regulation of angiogenesis; and negative regulation of endothelial cell proliferation. Predicted to be located in membrane and nuclear envelope. Is expressed in several structures, including brain; connective tissue; limb; musculoskeletal system; and spinal cord. Orthologous to human TNMD (tenomodulin). PHENOTYPE: Homozygous females exhibit a decrease in tenocyte proliferation and tendons have a greater variation of collagen fibril calibers exhibiting increased maximal diameters. [provided by MGI curators] |