Primary Identifier | MGI:1914814 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 67564 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables acetylcholine receptor regulator activity. Involved in chaperone-mediated protein complex assembly and positive regulation of protein localization to cell surface. Located in endoplasmic reticulum. Is expressed in adrenal gland; maturing glomerular tuft; nervous system; neural retina; and testis. Orthologous to human TMEM35A (transmembrane protein 35A). PHENOTYPE: Knockout causes a reduction in hippocampal long-term potentiation, which results in impairment of fear learning and long-term spatial reference memory. [provided by MGI curators] |