Primary Identifier | MGI:2685231 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 209540 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Is expressed in several structures, including eye; gonad; immune system; liver; and lung. Orthologous to human RTL9 (retrotransposon Gag like 9). PHENOTYPE: Homozygous mice lacking the C-terminal retroviral GAG-like region show impaired innate antifungal immunity showing loss of fungal zymosan degradation in microglial lysosomes. [provided by MGI curators] |