| Primary Identifier | MGI:2159566 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 170738 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable heme binding activity and inward rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of membrane potential. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including heart; mandibular process epithelium; nervous system; retina; and skin. Orthologous to human KCNH7 (potassium voltage-gated channel subfamily H member 7). PHENOTYPE: Homozygous knock-out mice exhibit depressive-like behavior with reduced locomotor activity, decreased digging behavior, and shorter latencies to fall off a rotating wheel and hyperexcitability with increased action potential firing in cerebellar Purkinje cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
