| Primary Identifier | MGI:2446854 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 237175 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion; facial ganglion; foot; hand; and trigeminal ganglion. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens. Orthologous to human ADGRG2 (adhesion G protein-coupled receptor G2). PHENOTYPE: Hemizygous null male mice display reduced fertility, oligozoospermia, teratozoospermia, asthenozoospermia, abnormal epididymis morphology, and abnormal fluid accumulation resulting in enlarged testes and dilated seminiferous tubules. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
